Abstract: Based on the case study of Tianjin metro Line 7, the response of an overpass to adjacent tunneling-induced loads is studied. A novel model is adopted that can efficiently consider the external load upon pile, superstructure constraint, ultimate pile-soil interactions in layered soils, and local soil behavior (elastic perfectly-plastic). In this model, pile groups are simplified as an Euler-Bernoulli beam lying on a half-space elastic continuum, and the elasto-plastic behavior of pile-soil interaction is realized by introducing plastic sliders into a pile-spring system. The classical elastic theory is extended into the layered soil by using the elastic layered soil solution, and the behavior of pile groups with rigid pile cap is considered by taking cap boundary conditions into the global stiffness matrix. The proposed two-stage method is verified through a comparison with the published results obtained by the boundary element method and filed measured data. Thereafter, the method is used to study the behavior of overpass to adjacent tunnel excavation. Results show that the impact of layered soil and soil yielding is significant. Analyses of pile groups with rigid cap confirm that the pile-cap connection decreases the tunneling-induced differential settlement; however, their action worsens the pile distress with respect to the bending moment. Also, this method is utilized for a parametric study to get a comprehensive understanding of cap response. Results show that the settlement of cap increases as the horizontal offset increases, whereas the horizontal displacement and the inclination of cap increase first to the maximum and then decrease gradually. With the increase of volume loss of tunnel and tunnel depth, the value of N-M indicates that the risk of local failure of unreinforced concrete piles increases. Further, the reinforced concrete is possibly damaged when the volume loss ratio exceeds 4% and the tunnel depth reaches 35 m.