Abstract: To enhance the energy absorption capacity and deformation stability of thin-walled energy-absorbing structures under lightweight conditions, a novel Auxetic Multi-Cell Tube (AMCT) is proposed. The AMCT incorporates auxetic unit cells into a conventional multi-cell thin-walled tube, combining the deformation coordination of auxetic units with the internal constraint effect of multi-cell structures, thereby improving the crushing stability and the energy absorption performance. AMCT specimens were fabricated using stereolithography 3D printing technology and experimentally investigated under quasi-static axial compressions. In parallel, a finite element model was established to obtain the mechanical response and deformation modes through numerical simulations. A good agreement between the experimental results and numerical simulations validates the effectiveness of the finite element model proposed. On this basis, the effects of the structural height and of the wall thickness on the energy absorption performance of the AMCT were analyzed, with the Auxetic Single-Cell Tube (ASCT) used as the primary comparison object; conventional Single-Cell Tube (SCT) and Multi-Cell Tube (MCT) were also introduced as reference structures to compare the axial compression responses and energy absorption performances of different structural forms. The research results indicate that increasing the structural height mainly contributes to an improvement in the total energy absorption of the AMCT, while its influence on the specific energy absorption is relatively limited. As the wall thickness increases, the load-carrying capacity, the total energy absorption and, the specific energy absorption of the AMCT are all significantly enhanced. Furthermore, under comparable mass conditions, the AMCT exhibits a more stable load response, higher specific energy absorption, and higher crush force efficiency than the those of ASCT. Although the conventional MCT shows relatively high load-carrying capacity and energy absorption efficiency, the AMCT presents a more gradual load increase in the initial compression stage, indicating its potential for cushioning and energy absorption. These findings provide a reference for the multi-cell design and for the optimization of auxetic thin-walled energy-absorbing structures.