Abstract: To address the challenges of excessive post-earthquake residual deformations in conventional reinforced concrete (RC) frames and severe damage to nonstructural partition walls, a resilience enhancement strategy combining self-centering technology with low-damage partition walls is proposed. Within a performance-based assessment framework, four configurations are established by cross-combining conventional/self-centering RC frames with conventional/low-damage partition walls. The study employs incremental dynamic analysis coupled with Monte Carlo simulations to systematically quantify the economic loss and repair time of different technical schemes under design-level and rare earthquakes. Results indicate that, for the case study, self-centering frames markedly reduce the residual interstory drifts under rare earthquakes to below 0.2%, lowering the demolition probability from 8.27% (conventional) to 0.09% and substantially mitigating the post-earthquake demolition loss. Low-damage partition walls, through flexible connections, effectively isolate the damage to nonstructural components, reducing the repairable loss by 20% and shortening the functional recovery time by 25% under design-level earthquakes. The combined application of both technologies provides a tiered, complementary disaster-mitigation mechanism, achieving a minimal expected loss across a broad seismic intensity range. These findings elucidate the differentiated contributions and synergy of structural and nonstructural components under various seismic risk levels, offering a theoretical basis for refined RC frame resilience design.