Abstract: To investigate the wind-induced vibration control performance of a tuned liquid column vibration absorber (TLCVA) system for tall buildings, a real-time hybrid simulation test (RTHST) on the wind-induced vibration control of the TLCVA system-tall building structure was carried out based on the established RTHST platform. Taking the third-generation benchmark model for the wind-induced vibration control of the structure as an example, the effectiveness of the developed RTHT system was validated by comparing the numerical simulation results with those of the RTHST. The structural control efficiency of the TLCVA system on the wind-induced responses of the studied tall building was investigated, with a particular attention to the influence of the excitation direction and of the wind speed period on its wind-induced response. The research results showed that: The TLCVA system can effectively mitigate the wind-induced responses (including structural acceleration, velocity, and displacement) of tall buildings under different excitation directions; For the investigated benchmark model, while the structural control efficiency of the TLCVA system slightly varies with the excitation direction, the variation is minimal; The TLCVA system exhibits more control efficiency for the acceleration response than those for the wind-induced velocity and displacement responses.