Abstract: Big-span power transmission tower is a high flexible structure. It is sensitive to dynamic load, especially to wind, which would cause significant dynamic response. Theoretically and economically, it is an important research issue for both power engineering and civil engineering to control the vibration of the big-span power transmission tower. This paper focuses on the behavior of Jingdongnan-Nanyang -Jingmen 1000kV transmission tower line across the Hanjiang river, which is one of the Eleventh-five National Key engineering project. The paper introduces the application of the lead viscoelastic damper (LVD) in controlling wind-induced vibration of big-span transmission towers, the wind field simulation technique and the effects of wind-induced vibration control under different wind directions. The effects of wind-induced vibration control are verified through examining LVD deformation, the contribution of stiffness, the response under simplified wind load and the reliability of the transmission tower. From the displacement and internal force of the main material under five different wind directions, the efficiency of the controlling scheme is also demonstrated, it would provide more experience for the engineering application in the future.